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Recombinant TARDBP 抗体 (pSer409, pSer410)

The 兔 单克隆 anti-TARDBP antibody (Clone 6M10) (ABIN7938522) specifically detects TARDBP in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7938522
发货至: 中国
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Quick Overview for Recombinant TARDBP 抗体 (pSer409, pSer410) (ABIN7938522)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

抗体类型

Recombinant Antibody

适用

  • 143
  • 85
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  • 23
  • 8
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  • 1
人, 小鼠

宿主

  • 132
  • 29
  • 1

克隆类型

  • 82
  • 80
单克隆

标记

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  • 8
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  • 5
  • 5
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  • 1
  • 1
  • 1
  • 1
  • 1
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This TARDBP antibody is un-conjugated

应用范围

  • 137
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  • 14
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  • 4
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Western Blotting (WB)

克隆位点

6M10
  • 抗原表位

    • 15
    • 14
    • 12
    • 8
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer409, pSer410

    原理

    TDP43 phospho Ser409/410 antibody (rAb), 100 μg (Clone 6M10)

    纯化方法

    Protein A Chromatography

    免疫原

    This information is proprietary to Active Motif and/or its suppliers.

    亚型

    IgG
  • 应用备注

    WB: 1:5000-1:50000 dilution

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TDP43

    背景

    TDP-43) was first isolated as a transcriptional inactivator binding to the TAR DNA element of the HIV-1 virus. Neumann et al. (2006) found that a hyperphosphorylated, ubiquitinated, and cleaved form of TARDBP, known as pathologic TDP-43, is the major component of the tau-negative and ubiquitin-positive inclusions that characterize amyotrophic lateral sclerosis (ALS) and the most common pathological subtype of frontotemporal lobar degeneration (FTLD-U).

    分子量

    43 kDa

    NCBI登录号

    NM_007375

    途径

    Positive Regulation of Peptide Hormone Secretion
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