Recombinant TARDBP 抗体 (C-Term)
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北京 101111
Quick Overview for Recombinant TARDBP 抗体 (C-Term) (ABIN7938519)
抗原
See all TARDBP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- TARDBP (C-terminal) (rAb), 100 μg (Clone 5D17)
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纯化方法
- Protein A Chromatography
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免疫原
- This information is proprietary to Active Motif and/or its suppliers.
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亚型
- IgG
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibodyTARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKD Validated TARDBP 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4730 unconjugated Recombinant Antibody
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:5000-1:50000 dilution IHC: 1:1000-1:4000 dilution
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TARDBP
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背景
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Background_Plain: TARDBP (TAR DNA-binding protein 43) also known as ALS10 and TDP-43. TARDBP is a RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs. In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases. In addition, TARDBP also has a variety of biological functions, such as plays a role in maintaining mitochondrial homeostasis by regulating the processing of mitochondrial transcripts, regulates also mRNA stability, participates also in the normal skeletal muscle formation and regeneration, negatively regulates the expression of CDK6 and regulates the expression of HDAC6, ATG7 and VCP in a PPIA/CYPA-dependent manner.
Aliases: TAR DNA-binding protein 43, ALS10, TDP-43
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分子量
- 43 kDa
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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