Recombinant MSH3 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant MSH3 抗体 (ABIN7938356)
抗原
See all MSH3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- MSH3 antibody (rAb), 100 μg (Clone 1J23)
-
纯化方法
- Protein A Chromatography
-
免疫原
- This antibody was raised against the MSH3 fusion protein.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:5000-1:10000 dilution
-
限制
- 仅限研究用
-
-
-
缓冲液
- Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
- MSH3 (MutS Homolog 3 (MSH3))
-
别名
- MSH3
-
背景
-
Background_Plain: MSH3 is a DNA mismatch repair (MMR) gene that heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. It undergoes frequent somatic mutation in colorectal cancers (CRCs) with MMR deficiency. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
Aliases: MutS Homolog 3, FAP4
-
分子量
- 127 kDa
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-