Histone H2A 抗体 (C-Term)
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Quick Overview for Histone H2A 抗体 (C-Term) (ABIN7938171)
抗原
See all Histone H2A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Histone H2A.Z.2.2 antibody (mAb) (Clone 1H11-11), sample
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纯化方法
- Protein G Chromatography
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免疫原
- This antibody was raised against a peptide within the C-terminal region of human Histone H2A.Z.2.2.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- Histone H2A
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别名
- Histone H2A.
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背景
- Histone H2A.Z (H2A Histone Family, Member V) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle. H2A.Z is acetylated at multiple lysine residues in its amino terminus, which may serve to allow H2A.Z to function as an insulator of chromatin domains. In the case of H2A.Z.2.2, this variant has been shown to be responsible for destabilization of the nucleosome through the chaperone complexes TIP60 and SRCAP.
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分子量
- 12 kDa
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NCBI登录号
- NP_619541
抗原
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