Recombinant Histone H2A 抗体 (H2A.XS139ph)
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Quick Overview for Recombinant Histone H2A 抗体 (H2A.XS139ph) (ABIN7938169)
抗原
See all Histone H2A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- H2A.XS139ph
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原理
- Histone H2A.XS139ph antibody (rAb) (H2AX) (Clone RM224)
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纯化方法
- Protein A Chromatography
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免疫原
- A phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
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亚型
- IgG
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anti-Histone H2A (acLys9) antibody
适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (pSer139) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (H2AK95ac) antibody适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6080 unconjugated Recombinant Antibody
anti-Histone H2A (pThr120) antibody适用: 人 WB, IF, DB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (meGln104) antibody适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (ubLys119) antibody适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (AA 1-15) antibody适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (H2AK9ac) antibody适用: 人 ELISA, IF, ICC 宿主: 兔 Monoclonal 3H5 unconjugated Recombinant Antibody
anti-Histone H2A (AA 1-128) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Histone H2A (pThr121) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 0.5 - 2 μg/mL ICC: 0.5 - 2 μg/mL
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限制
- 仅限研究用
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缓冲液
- PBS with 50 % glycerol, 1 % BSA, and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- Histone H2A
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别名
- Histone H2A.
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背景
- Histone H2AX phospho Ser139 (H2AX, H2A histone family member X) replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries that require DNA as a template. Histones thereby play a central role in transcriptional regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called the histone code, and nucleosome remodeling. Histone H2AX is required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation, and for efficient repair of DNA double-strand breaks (DSBs), specifically when modified by C-terminal phosphorylation. RM224 reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
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NCBI登录号
- NP_002096
抗原
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