BRD2 抗体 (AA 58-232)
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Quick Overview for BRD2 抗体 (AA 58-232) (ABIN7938062)
抗原
See all BRD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 58-232
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原理
- BRD2 antibody (pAb)
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纯化方法
- Affinity Purified
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免疫原
- This BRD2 antibody was raised against a recombinant protein comprising amino acids 58-232 of human BRD2 (NP_005095 ).
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亚型
- IgG
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anti-Bromodomain Containing 2 (BRD2) (AA 227-364) antibody
BRD2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7C1B10 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 167-256) antibodyBRD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 524-573) antibodyBRD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 675-725) antibodyBRD2 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) antibodyBRD2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB1645 unconjugated Recombinant Antibody
anti-Bromodomain Containing 2 (BRD2) (AA 170-200) antibodyBRD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3416 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 227-364) antibodyBRD2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H6B12 unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 1-801) antibodyBRD2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 675-725) antibodyBRD2 适用: 人 IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 2 (BRD2) (AA 675-725) antibodyBRD2 适用: 人, 小鼠 WB, IP, FACS 宿主: 兔 Monoclonal BL-167-2A2 unconjugated Recombinant Antibody
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应用备注
- ChIP-Seq: 6 µL per ChIP CUT&RUN: 1 µL per 50 µL reaction
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限制
- 仅限研究用
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缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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储存条件
- -20 °C
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储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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有效期
- 24 months
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- BRD2 (Bromodomain Containing 2 (BRD2))
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别名
- BRD2
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背景
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Background_Plain: BRD2 (Bromodomain-containing protein 2) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of at least four members in mouse and human, BRD2 (also referred to as FSRG1, RING3), BRD3 (FSRG2, ORFX), BRD4 (FSRG4, MCAP/HUNK1), and BRDT (FSRG3, BRD6). BRD proteins are related to the female Sterile Homeotic protein in Drosophila, a gene required maternally for proper expression of other homeotic genes, such as Ubx, which is involved in pattern formation. BRD2 causes elevated protein kinase activity in leukemias. Transgenic mice overexpressing BRD2 in the lymphoid system develop diffuse large-cell lymphoma. BRD2 has been shown to interact with E2F1 and with histone H4 acetylated at Lys12 via its two bromodomains. BRD2 may play a role in spermatogenesis or folliculogenesis. Genetic evidence links the BRD2 gene to both juvenile myoclonic epilepsy and photoparoxysomal responses.
Aliases: Bromodomain Containing 2, O27.1.1, RING3
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分子量
- 110 kDa
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NCBI登录号
- NP_005095
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途径
- Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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