N6-Methyladenosine 抗体
Our Local Distributor
北京 101111
Quick Overview for N6-Methyladenosine 抗体 (ABIN7938032)
抗原
宿主
克隆类型
标记
应用范围
-
-
原理
- N6-Methyladenosine (m6A) antibody (pAb)
-
纯化方法
- Protein A Chromatography
-
免疫原
- This antibody was raised against 6-Methyladenosine conjugated to KLH.
-
亚型
- IgG
-
-
-
-
应用备注
- DB: 1 - 2 μg/mL dilution For N6-Methyladenosine (m6A), we also offer AbFlex N6-Methyladenosine (m6A) Recombinant Antibody (rAb). For details, see Catalog No. 91261.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
-
储存条件
- -20 °C
-
储存方法
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
有效期
- 24 months
-
-
- N6-Methyladenosine
-
物质类
- Chemical
-
背景
- N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.
抗原
-