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N6-Methyladenosine 抗体

This 小鼠 单克隆 antibody specifically detects N6-Methyladenosine in DB 和 IP. It exhibits reactivity toward 人 和 Saccharomyces cerevisiae.
产品编号 ABIN7938031
发货至: 中国
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Quick Overview for N6-Methyladenosine 抗体 (ABIN7938031)

抗原

N6-Methyladenosine

适用

  • 3
  • 2
  • 1
人, Saccharomyces cerevisiae

宿主

  • 12
  • 3
小鼠

克隆类型

  • 13
  • 2
单克隆

标记

  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 15
  • 12
  • 9
  • 1
  • 1
Dot Blot (DB), Immunoprecipitation (IP)

克隆位点

17-3-4-1
  • 原理

    N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1), sample

    纯化方法

    Protein A Chromatography

    免疫原

    This antibody was raised against 6-Methyladenosine conjugated to BSA.

    亚型

    IgG1 kappa
  • 应用备注

    For N6-Methyladenosine (m6A), we also offer an AbFlex N6-Methyladenosine (m6A) Recombinant Antibody (rAb). For details, see Catalog No. 91261.

    限制

    仅限研究用
  • 缓冲液

    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • 抗原

    N6-Methyladenosine

    物质类

    Chemical

    背景

    N6-Methyladenosine (m6A) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well.
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