CRTC1 抗体 (pSer151) (Biotin)
Quick Overview for CRTC1 抗体 (pSer151) (Biotin) (ABIN746560)
抗原
See all CRTC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer151
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特异性
- Due to the highly conserved nature of this protein, this antibody will react with Torc3 when phosphorylated at Ser162 across the listed species due to homology.
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交叉反应
- 小鸡, 人
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预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151
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亚型
- IgG
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anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (pSer151) antibody
CRTC1 适用: 人, 小鸡 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, IP, FACS, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1B5 unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 1-248) antibodyCRTC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 553-634) antibodyCRTC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) antibodyCRTC1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 1 (CRTC1) (AA 1-200) antibodyCRTC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
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别名
- Torc1
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背景
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Synonyms: MECT1, TORC1, TORC-1, WAMTP1, CREB-regulated transcription coactivator 1, Mucoepidermoid carcinoma translocated protein 1, Transducer of regulated cAMP response element-binding protein 1, Transducer of CREB protein 1, CRTC1, KIAA0616
Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
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基因ID
- 23373
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UniProt
- Q6UUV9
抗原
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