Tuberin 抗体 (pThr1462)
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- 抗原 See all Tuberin (TSC2) 抗体
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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抗原表位
- pThr1462
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Tuberin antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462
- 亚型
- IgG
- Top Product
- Discover our top product TSC2 Primary Antibody
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anti-Tuberous Sclerosis 2 (TSC2) (AA 1611-1807) antibody
TSC2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibodyTSC2 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13393 unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibodyTSC2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) antibodyTSC2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibodyTSC2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr927) antibodyTSC2 适用: 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (AA 1396-1496) antibodyTSC2 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibodyTSC2 适用: 人 DB 宿主: 兔 Polyclonal RB13340 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
- 别名
- TSC2 (TSC2 产品)
- 别名
- TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
- 背景
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Synonyms: Tuberinphospho T1462, Tuberin phospho Thr1462, p-Tuberin Thr1462, FLJ43106, LAM, OTTHUMP00000158940, OTTHUMP00000198394, OTTHUMP00000198395, TSC2, TSC2_HUMAN, TSC4, Tuberin, Tuberous sclerosis 2, Tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog.
Background: Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.
- 基因ID
- 7249
- 途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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