RPS6KA2 抗体 (pSer360, pThr356)
Our Local Distributor
北京 101111
Quick Overview for RPS6KA2 抗体 (pSer360, pThr356) (ABIN745253)
抗原
See all RPS6KA2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer360, pThr356
-
预测反应
- Human,Mouse,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic phosphopeptide derived from human RSK3 around the phosphorylation site of Thr356/Ser360
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
-
别名
- RSK3 +
-
背景
-
Synonyms: 90 kDa ribosomal protein S6 kinase 2, HU 2, KS6A2_HUMAN, MAP kinase activated protein kinase 1c, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, MAPKAPK1C, p90-RSK 2, p90RSK 2, p90RSK2, pp90RSK 3, pp90RSK3, Ribosomal protein S6 kinase alpha-2, Ribosomal S6 kinase 3, RPS6KA2, RSK 3, RSK-3, S6K alpha 2, S6K alpha, S6K-alpha-2.
Background: RSK3(Ribosomal S6 kinase 3)is a member of a family of 90- kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2. Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, phosphorylates potential nuclear targets and may have a unique upstream activator. Several sites, such as Ser380, Thr359, Ser363 and Thr573, are important for its activation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
-
基因ID
- 6196
-
途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-