电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

S1PR1 抗体 (Extracellular, N-Term)

This 兔 多克隆 antibody specifically detects S1PR1 in WB, IF, IHC, FACS, LCI 和 IC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7885536
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for S1PR1 抗体 (Extracellular, N-Term) (ABIN7885536)

抗原

See all S1PR1 抗体
S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

适用

  • 97
  • 64
  • 44
  • 7
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 95
  • 10

克隆类型

  • 85
  • 20
多克隆

标记

  • 58
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This S1PR1 antibody is un-conjugated

应用范围

  • 76
  • 39
  • 20
  • 16
  • 14
  • 14
  • 13
  • 12
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Live Cell Imaging (LCI), Immunochromatography (IC)

质量等级

Carrier-free
  • 抗原表位

    • 15
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-30, Extracellular, N-Term

    原理

    A Rabbit Polyclonal Antibody to Sphingosine 1-Phosphate Receptor 1

    预测反应

    Mouse,rat - 13,14 amino acid residues identical

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    SDYVNYDIIVRHYN(C), corresponding to amino acid residues 17-30 of human S1PR1

    亚型

    IgG
  • 应用备注

    WB: 1:200

    FC: 5 mg per reaction

    ICC: 1:50

    IHC: 1:100

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7237267)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

    别名

    Sphingosine 1-phosphate receptor 1

    背景

    Synonyms: Sphingosine 1-phosphate receptor 1, S1P1, Endothelial differentiation G-protein coupled receptor 1, CD363, CHEDG1

    Description: Lysophospholipids constitute a group of important lipid mediators, lysophosphatidic acid (LPA) a glycerolysophospholipid and sphingosine 1-phosphate (S1P), a lysosphingolipid. Sphingosine 1-phosphate is a bioactive lipid derived from metabolism of sphingomyelin1. Sphingosine 1-phosphate is implicated in the regulation of many cellular functions including proliferation, apoptosis, survival, adhesion, differentiation, and migration2. Sphingosine 1-phosphate exerts its activity through five distinct G-protein-coupled receptors, (also named endothelial differentiation gene receptors - EDG), S1PR1 (EDG-1), S1PR2 (EDG-5), S1PR3 (EDG-3), S1PR4 (EDG-6), and S1PR5 (EDG-8)3.Sphingosine 1-phosphate receptor 1 (S1PR1) is ubiquitously expressed. S1PR1 mRNA is detected in the brain, heart, spleen, liver, lung, thymus, kidney, skeletal muscle and lymphoid tissues4. Knockout of the gene encoding S1PR1 is lethal and therefore makes in vivo studies difficult5.

    基因ID

    1901

    UniProt

    P21453

    途径

    Signaling Events mediated by VEGFR1 and VEGFR2
You are here: