Prokineticin Receptor 2 抗体 (Extracellular, N-Term)
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Quick Overview for Prokineticin Receptor 2 抗体 (Extracellular, N-Term) (ABIN7885322)
抗原
See all Prokineticin Receptor 2 (PROKR2) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 3-15, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Prokineticin Receptor 2
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预测反应
- Mouse - 11,13 amino acid residues identical, human - 9
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)DQNGNTSFAPDLN, corresponding to amino acid residues 3-15 of rat PROKR2
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亚型
- IgG
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anti-Prokineticin Receptor 2 (PROKR2) antibody
PROKR2 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (Internal Region) antibodyVerified PROKR2 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (N-Term) antibodyPROKR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (AA 121-136) antibodyPROKR2 适用: 人, 小鼠, 大鼠 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 6D3B9 unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (acetylated) antibodyPROKR2 适用: 人, 小鼠 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 4E9B11 unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (AA 1-45) antibodyPROKR2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (C-Term) antibodyPROKR2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (AA 3-15), (Extracellular), (N-Term) antibodyKO Validated PROKR2 适用: 大鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (C-Term) antibodyPROKR2 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 2 (PROKR2) (N-Term) antibodyPROKR2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236613)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Prokineticin Receptor 2 (PROKR2)
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别名
- PROKR2
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背景
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Synonyms: PROKR2, PKR2, G-protein coupled receptor 73-like 1, Gpr73l1, Gpr73b, G-protein coupled receptor I5E
Description: The Prokineticins (PK1 and PK2) are a pair of cysteine-rich secreted peptides with broad physiological functions including gastrointestinal motility, angiogenesis, hematopoiesis and circadian rhythms regulation.The biological effects of PK1 and PK2 are mediated by two highly homologous receptors termed Prokineticin receptor 1 (PKR1) and Prokineticin receptor 2 (PKR2) that belong to the 7-transmembrane domain, G-protein coupled receptor (GPCR) superfamily. Both PK ligands activate the two PK receptors with similar potency.1PKR2 receptors couple to Gq/G11 proteins leading to phospholipase C activation, inositol phosphate production and calcium mobilization.The distribution of PKR2 is relatively restricted with high expression levels in the brain, spinal cord and dorsal root ganglions, in organs of the reproductive system and in endocrine tissues such as the thyroid, pituitary and adrenal glands.1The PK2 ligand has been shown to be involved in the regulation of circadian rhythms of physiological and behavioral processes in mammals, probably through signaling via PKR2 which is highly expressed in the suprachiasmatic nucleus (SCN), an area of the brain that controls circadian rhythm processes.2In addition, loss-of-function mutations in the PKR2 gene have been associated with Kallmann Syndrome, a condition characterized by idiopathic hypogonadotropic hypogonadism (IHH) in combination with anosmia, a compromised sense of smell.3
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基因ID
- 192649
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UniProt
- Q8R415
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途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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