Prokineticin Receptor 1 抗体 (Extracellular, N-Term)
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Quick Overview for Prokineticin Receptor 1 抗体 (Extracellular, N-Term) (ABIN7885321)
抗原
See all Prokineticin Receptor 1 (PROKR1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 10-24, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Prokineticin Receptor 1
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预测反应
- Mouse - 12,15 amino acid residues identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)ENTTNTFTDFFSARD, corresponding to amino acid residues 10-24 of rat PROKR1
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亚型
- IgG
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anti-Prokineticin Receptor 1 (PROKR1) (AA 10-24), (Extracellular), (N-Term) antibody
PROKR1 适用: 大鼠 WB, IHC, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) (N-Term) antibodyPROKR1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) (N-Term) antibodyPROKR1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) (N-Term) antibodyPROKR1 适用: 人 WB, FACS, EIA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) (N-Term) antibodyPROKR1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) (AA 1-62) antibodyPROKR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) antibodyPROKR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prokineticin Receptor 1 (PROKR1) (N-Term) antibodyPROKR1 适用: 人, 小鼠 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236609)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Prokineticin Receptor 1 (PROKR1)
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别名
- PROKR1
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背景
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Synonyms: PROKR1, PKR1, G-protein coupled receptor 73, Gpr73, Gpr73a, G-protein coupled receptor ZAQ
Description: The Prokineticins (PK1 and PK2) are a pair of cysteine-rich secreted peptides with broad physiological functions including gastrointestinal motility, angiogenesis, hematopoiesis and circadian rhythms regulation.The biological effects of PK1 and PK2 are mediated by two highly homologous receptors termed Prokineticin receptor 1 (PKR1) and Prokineticin receptor 2 (PKR2) that belong to the 7-transmembrane domain, G-protein coupled receptor (GPCR) superfamily. Both PK ligands activate the two PK receptors with similar potency.1PKR1 receptors couple to Gq/G11 proteins leading to phospholipase C activation, inositol phosphate production and calcium mobilization. In addition, activation of the mitogen-activated protein kinase (MAPK) pathways has also been described.1PKR1 is broadly distributed throughout peripheral tissues including the intestinal tract, testis, uterus, lung and peripheral blood leukocytes. In addition, the receptor is expressed in the brain, particularly in olfactory regions, as well as in dorsal root ganglion (DRG) neurons.The physiological function of PKR1 is still being elucidated, however, evidence suggest that the receptor has an important role in pain perception through its ability to stimulate the TRPV1 ion channel in DRG neurons.2In addition, a role for PKR1 in the control of the inflammatory response through regulation of macrophage chemotaxis and cytokine production has also been demonstrated.3
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基因ID
- 192648
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UniProt
- Q8R416
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途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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