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KISS1R 抗体 (3rd Extracellular Loop)

The 兔 多克隆 anti-KISS1R antibody is suitable to detect KISS1R in samples from 人 和 小鼠. It has been validated for WB, IHC, IF, FACS 和 LCI.
产品编号 ABIN7885102
发货至: 中国
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Quick Overview for KISS1R 抗体 (3rd Extracellular Loop) (ABIN7885102)

抗原

See all KISS1R 抗体
KISS1R (KISS1 Receptor (KISS1R))

适用

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人, 小鼠

宿主

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克隆类型

  • 54
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多克隆

标记

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This KISS1R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)

质量等级

Carrier-free
  • 抗原表位

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    3rd Extracellular Loop, AA 292-305

    原理

    A Rabbit Polyclonal Antibody to Kisspeptin Receptor

    预测反应

    mouse - 12,14 amino acid residues identical,Rat - 13

    纯化方法

    Affinity purified on immobilized antigen.

    免疫原

    (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

    亚型

    IgG
  • 应用备注

    WB: 1:500

    FC: The optimal concentration should be determined by the user

    ICC: The optimal concentration should be determined by the user

    IHC: 1:100

    IP: The optimal concentration should be determined by the user

    说明

    Negative Control: (ABIN7235833)

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    0.2 mL double distilled water (DDW)

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
  • 抗原

    KISS1R (KISS1 Receptor (KISS1R))

    别名

    Kisspeptin receptor

    背景

    Synonyms: Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12

    Description: The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

    基因ID

    84634

    UniProt

    Q969F8
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