HRH2 抗体 (2nd Extracellular Loop)
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Quick Overview for HRH2 抗体 (2nd Extracellular Loop) (ABIN7885078)
抗原
See all HRH2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- 2nd Extracellular Loop
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原理
- A Rabbit Polyclonal Antibody to Histamine H2 Receptor
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预测反应
- Mouse - identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- RNGTRGGNDTFKC, corresponding to amino acids 161-173 of rat HRH2
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亚型
- IgG
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anti-Histamine Receptor H2 (HRH2) (C-Term) antibody
Verified HRH2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (N-Term) antibodyHRH2 适用: 人 WB, IF, IHC, IHC (p), ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 161-259) antibodyHRH2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 309-323) antibodyVerified HRH2 适用: 大鼠, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Cytoplasmic Domain) antibodyHRH2 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (2nd Extracellular Loop) antibodyHRH2 适用: 大鼠 WB, IF, IHC, FACS, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Internal Region) antibodyHRH2 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Extracellular Domain) antibodyHRH2 适用: 人, 大鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (AA 150-250) antibodyHRH2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Histamine Receptor H2 (HRH2) (Center) antibodyHRH2 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 1:20
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235754)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- HRH2 (Histamine Receptor H2 (HRH2))
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别名
- H2R
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背景
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Synonyms: H2R, HH2R, Gastric receptor I, Gastric receptor 1
Description: Histamine (2-[4-imidazole]ethylamine) is a low-molecular-weight amine synthesized from L-histidine. It is produced by various cells throughout the body, including central nervous system neurons, gastric mucosa parietal cells, mast cells, basophils and lymphocytes. Histamine is a major biological mediator whose functions include, among many others, regulation of vascular smooth muscle, immune regulation, regulation of sleep-wake cycles and regulation of gastric acid secretion.1,2The biological effects of histamine are mediated through four receptors (H1-H4 receptors) all of which belong to the 7-transmembrane domain, G protein-coupled receptor (GPCR) superfamily.H2 receptors couple to adenylate cyclase via Gs, leading to the formation of cAMP and the activation of protein kinase A (PKA).1,2 H2 receptors are expressed in several tissues including the brain, gastrointestinal tract and heart.The most studied physiological role of the H2 receptor is its involvement in the regulation of gastric acid secretion.3 Specific H2 receptor antagonists are currently used for the treatment of acid-related gastrointestinal conditions such as peptic ulcer, gastroesophageal reflux disease and dyspepsia.Involvement of H2 receptors in chronic heart failure and immune regulation has also been suggested.
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基因ID
- 25461
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UniProt
- P25102
抗原
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