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HRH2 抗体 (N-Term)

HRH2 适用: 人 WB, IF, IHC (p), IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856570
发货至: 中国
  • 抗原 See all HRH2 抗体
    HRH2 (Histamine Receptor H2 (HRH2))
    抗原表位
    • 13
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 51
    • 26
    • 25
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 2
    克隆类型
    • 54
    多克隆
    标记
    • 25
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HRH2 antibody is un-conjugated
    应用范围
    • 49
    • 24
    • 8
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    交叉反应
    人, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Histamine H2 Receptor (histamine receptor H2)
    Histamine H2 Receptor antibody [N1], N-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histamine H2 Receptor. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product HRH2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: NT2D1 , PC-3 , U87-MG , SK-N-SH

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.75 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Adderley, Zhang, Breslin: "Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction." in: Microcirculation (New York, N.Y. : 1994), Vol. 22, Issue 4, pp. 237-48, (2016) (PubMed).

    Kurtz, Moor, Souza-Smith, Breslin: "Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics." in: Microcirculation (New York, N.Y. : 1994), Vol. 21, Issue 7, pp. 593-605, (2015) (PubMed).

  • 抗原
    HRH2 (Histamine Receptor H2 (HRH2))
    别名
    histamine receptor H2 (HRH2 产品)
    别名
    H2R antibody, HH2R antibody, HRH2 antibody, histamine receptor H2 antibody, histamine receptor H2a antibody, histamine receptor H 2 antibody, HRH2 antibody, Hrh2 antibody, hrh2a antibody
    背景
    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Cell membrane, Multi-pass membrane protein
    分子量
    40 kDa
    基因ID
    3274
    UniProt
    P25021
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