Chloride Channel 5 抗体 (Extracellular)
Our Local Distributor
北京 101111
Quick Overview for Chloride Channel 5 抗体 (Extracellular) (ABIN7884875)
抗原
See all Chloride Channel 5 (CLCN5) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 401-415, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to CLC-5 (CLCN5) Channel
-
预测反应
- Mouse - identical, human - 14,15 amino acid residues identical
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLCN5
-
亚型
- IgG
-
-
-
-
应用备注
-
WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: BLP-CL003
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 0.2 mL double distilled water (DDW)
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- Chloride Channel 5 (CLCN5)
-
别名
- CLCN5
-
背景
-
Synonyms: CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS
Description: CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes, where it is believed to contribute to their acidification.The channel is mainly expressed in the kidney, although it has also been found in the small intestine, brain and liver.Mutations in the CLC5 gene cause Dent's disease, an X-linked renal disorder.
-
基因ID
- 25749
-
UniProt
- P51796
抗原
-