CNR1 抗体 (Extracellular, N-Term)
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Quick Overview for CNR1 抗体 (Extracellular, N-Term) (ABIN7884842)
抗原
See all CNR1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 84-99, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Cannabinoid Receptor 1
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预测反应
- Human - identical, mouse - 15,16 amino acid residues identical
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- NKSLSSFKENEENIQC, corresponding to amino acid residues 84-99 of rat CB1 receptor
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亚型
- IgG
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anti-Cannabinoid Receptor 1 (CNR1) (C-Term) antibody
CNR1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (Internal Region) antibodyVerified CNR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (N-Term) antibodyCNR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (AA 1-110) antibodyCNR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (AA 1-110) antibodyCNR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F9 unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (AA 73-122) antibodyCNR1 适用: 人, 大鼠, 猴, Cow, 豚鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (C-Term) antibodyCNR1 适用: 人, 大鼠, 小鼠, 猴, 犬, Cow, 马, Bat, Pig IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cannabinoid Receptor 1 (CNR1) antibodyMicroarray verified CNR1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB313026 unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (AA 1-75) antibodyCNR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cannabinoid Receptor 1 (CNR1) (AA 84-99), (Extracellular), (N-Term) antibodyCNR1 适用: 大鼠 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7235028)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW)
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- CNR1 (Cannabinoid Receptor 1 (CNR1))
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别名
- CB1
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背景
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Synonyms: CB1, CB-R, CNR1, CB1R, CANN6, Brain-type cannabinoid receptor, Central cannabinoid receptor
Description: Cannabinoids have been used in Eastern medicine for many years as pain relievers.1 Δ9-tetrahydrocannabinol (THC), the major psychoactive compound in marijuana and hashish, has been shown to interact with two specific cannabinoid receptors: cannabinoid receptor 1 (CB1 receptor) and cannabinoid receptor 2 (CB2 receptor).2 The cannabinoid receptors can be distinguished by their amino acid sequences, signaling mechanisms, and tissue distributions.2 Both receptors belong to the G-protein coupled receptor (GPCR) superfamily. CB1 was shown to modulate several Ca2+ and K+ ion channels.2,3CB1 is primarily expressed in the central nervous system. However, expression of CB1 is also detected in the peripheral terminals, in non-neuronal peripheral tissues such as uterus, testes, spleen, as well as in cells of the immune system.3,4CB1 is implicated in many cellular functions such as neurotransmitter release, pain relief, cancer, and obesity.5,6 Growth inhibition of tumor cells was demonstrated following mixed CB1/CB2 agonist treatment in both prostate and non-melanoma skin cancers.5,6 Through their interaction with CB1, cannabinoid compounds stimulate appetite for sweets and palatable foods in particular, making CB1 an attractive therapeutic target for the treatment of obesity and eating disorders.7
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基因ID
- 25248
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UniProt
- P20272
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途径
- Feeding Behaviour
抗原
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