Substance P 抗体
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北京 101111
Quick Overview for Substance P 抗体 (ABIN7884251)
抗原
See all Substance P 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Substance P Rat Monoclonal Antibody (NC1/34)
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特异性
- This antibody recognizes the COOH-terminal end of substance P. It does not recognize Leu- or Met enkephalin, somatostatin or beta-endorphin, cross-reactivity with eledoisin: 5 % . It recognizes Substance P in post-mortem tissue of the human brain.
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预测反应
- All Mammals
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免疫原
- Substance P
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亚型
- IgG2a
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anti-Substance P antibody
适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Substance P (AA 58-68) antibody适用: 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Substance P antibody适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal SP-DE4-21 unconjugated
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应用备注
- IHC and ICC 1:200,ICC 1:200
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- If reconstituted with deionized water in 0.5 mL: IHC and ICC 1:200 - 1:500. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized tissue culture supernatant
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- Substance P
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背景
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Substance P, tachykinin, neuropeptide, neurokinin, SP, anti-tachykinin, anti-neuropeptide, anti-neurokinin, anti-SP
The discovery of substance P (SP) was reported in 1931. After more than 70 years of investigation, SP is perhaps the best understood neuropeptide transmitter. Substance P is an undecapeptide, which by the mid-1980s was recognized to belong to the tachykinin peptide family, it is also member of the neurokinins. It has been proposed that SP, released from primary afferent nerve endings, plays a role in chronic inflammation and pain. Neurotransmitters appear to play a key role in the regulation of emotions and antagonists of their receptors may be novel psychotropic drugs of the future.
抗原
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