HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) (AA 579-613) 抗体
This Human 单克隆 antibody specifically detects HIV-1 Transmembrane Glycoprotein in ELISA, IP 和 ICo. It exhibits reactivity toward Human Immunodeficiency Virus (HIV).
产品编号 ABIN7884243
发货至:
中国
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Quick Overview for HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) (AA 579-613) 抗体 (ABIN7884243)
抗原
HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)
适用
Human Immunodeficiency Virus (HIV)
宿主
Human
克隆类型
单克隆
标记
非结合性
应用范围
ELISA, Immunoprecipitation (IP), Immunocompetition (ICo)
克隆位点
50-69
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抗原表位
- AA 579-613
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原理
- HIV-1 (gp41) Human Monoclonal Antibody (50-69)
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特异性
- The antibody recognizes the HIV-1 protein gp41. (amino acids 579-613)
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纯化方法
- Protein G purified
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免疫原
- The antibody was generated from HIV-infected individuals by a method based on the Epstein-Barr virus transformation of peripheral blood mononuclear cells (PBMCs) followed by fusion with heteromyeloma cells.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute with deionized water. Optimal dilution has to be determined by the user.
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缓冲液
- Lyophilized protein G purified in PBS pH 7.4
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.
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有效期
- 24 months
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- HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)
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别名
- HIV-1 (gp41)
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物质类
- Viral Protein
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背景
- Of the two types of Human immunodeficiency virus (HIV) which have been characterized, HIV-1 is more infective and is prevalent globally. The HIV virion is encapsulated by a viral envelope that contains complexes of surface proteins, which are important for the virus to attach and fuse to infect target cells. A precursor molecule known as gp160 (glycoprotein 160) is cleaved by proteases into gp120 (glycoprotein 120) and gp41 (glycoprotein 41), glycoproteins that make up the envelope proteins of HIV. Glycoprotein gp41 is embedded in the viral membrane and can interact with other gp41 proteins. The proteins gp41 and gp120 form a complex which is thought to undergo conformational changes in order to initiate membrane fusion of the virus with a cell.
抗原
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