Bax Inhibitor 1 抗体
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北京 101111
Quick Overview for Bax Inhibitor 1 抗体 (ABIN7882547)
抗原
See all Bax Inhibitor 1 (TMBIM6) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- BI-1 Antibody / Bax inhibitor 1 / TMBIM6
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序列
- RKINFDALLK FSHITPSTQQ HLK
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids RKINFDALLKFSHITPSTQQHLK were used as the immunogen for the BI-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BI-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the BI-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))
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别名
- BI-1
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背景
- Bax inhibitor 1 (BI-1) is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.
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UniProt
- P55061
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途径
- Response to Water Deprivation, ER-Nucleus Signaling
抗原
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