TSHB 抗体
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Quick Overview for TSHB 抗体 (ABIN7882485)
抗原
See all TSHB 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- TSHB Antibody / TSH beta (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein was used as the immunogen for this TSHB antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the TSHB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the TSHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
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别名
- TSHB
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背景
- The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
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UniProt
- P01222
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途径
- Thyroid Hormone Synthesis, Peptide Hormone Metabolism
抗原
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