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TEK 抗体

The 兔 多克隆 anti-TEK antibody (ABIN7882433) specifically detects TEK in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7882433
发货至: 中国
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Quick Overview for TEK 抗体 (ABIN7882433)

抗原

See all TEK 抗体
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

  • 137
  • 65
  • 50
  • 22
  • 4
  • 3
人, 小鼠, 大鼠

宿主

  • 121
  • 28
  • 5
  • 3
  • 1
  • 1

克隆类型

  • 125
  • 34
多克隆

标记

  • 84
  • 10
  • 9
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TEK antibody is un-conjugated

应用范围

  • 80
  • 59
  • 43
  • 40
  • 40
  • 33
  • 14
  • 13
  • 12
  • 11
  • 9
  • 7
  • 4
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    TEK Antibody / TIE2

    序列

    EALMNQHQDP LEVTQDVTRE WAKKVVWK

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids EALMNQHQDPLEVTQDVTREWAKKVVWK from the human protein were used as the immunogen for the TEK antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TEK antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TEK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    TEK

    背景

    TIE2, also known as TEK tyrosine kinase, is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.

    UniProt

    Q02763

    途径

    RTK signaling, Growth Factor Binding
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