Recombinant TARDBP 抗体
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北京 101111
Quick Overview for Recombinant TARDBP 抗体 (ABIN7882428)
抗原
See all TARDBP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TARDBP Antibody / TAR DNA binding protein 43 / TDP43
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纯化方法
- Affinity chromatography
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免疫原
- A peptide sequence specific to TAR DNA binding protein 43 was used as the immunogen for the TARDBP antibody.
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亚型
- IgG
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibodyTARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKD Validated TARDBP 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB4730 unconjugated Recombinant Antibody
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TARDBP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TARDBP Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TARDBP
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背景
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TARDBP encodes TDP-43, a DNA/RNA-binding protein that regulates pre-mRNA splicing, transcript stability, and RNA transport. It shuttles between nucleus and cytoplasm and recognizes UG-rich elements through 2 RNA recognition motifs (RRM1/RRM2), while a low-complexity, glycine-rich C-terminus supports proteinâ€""protein and ribonucleoprotein assembly. Through these activities, TDP-43 coordinates RNA processing programs that influence neuronal function and broader cell biology.
TDP-43 participates in stress-responsive ribonucleoprotein remodeling and interacts with components of transcription, splicing, and translation pathways. Changes in localization, solubility, or post-translational status are widely monitored as readouts in studies of RNA metabolism, proteostasis, and cellular stress adaptation across model systems.
The TARDBP antibody enables specific detection of endogenous TDP-43 in applications such as western blot, immunofluorescence, immunohistochemistry, and immunoprecipitation. Researchers use the TARDBP antibody from NSJ Bioreagents to quantify total protein, assess nuclearâ€""cytoplasmic distribution, and evaluate biochemical fractionation outputs. With high specificity and consistent performance, the TARDBP antibody supports rigorous analysis of RNA-binding protein networks and RNA processing dynamics.
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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