STUB1 抗体 (C-Term)
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北京 101111
Quick Overview for STUB1 抗体 (C-Term) (ABIN7882378)
抗原
See all STUB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- STUB1 Antibody (C-Terminal Region)
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纯化方法
- Protein G purified
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免疫原
- Recombinant human STUB1 was used as the immunogen for the STUB1 antibody.
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亚型
- IgG1, kappa
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anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibody
STUB1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (C-Term) antibodyVerified STUB1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) antibodySTUB1 适用: 人, 小鼠, 大鼠, 猴, Cow, 豚鼠, 犬, Pig, 马, 小鸡, Hamster, Avian, Cat, 驴, 山羊, 兔, 绵羊 WB, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 51-303) antibodySTUB1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS 宿主: 小鼠 Monoclonal 13I8 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231) antibodySTUB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 203-231), (C-Term) antibodySTUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7393 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) antibodySTUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 236-263), (C-Term) antibodySTUB1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB32217 unconjugated
anti-STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-48) antibodySTUB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the STUB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles
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储存条件
- -20 °C
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储存方法
- Aliquot the STUB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
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别名
- STUB1
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背景
- E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF- BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation. [UniProt]
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UniProt
- Q9UNE7
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途径
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
抗原
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