SPOP-B 抗体
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Quick Overview for SPOP-B 抗体 (ABIN7882341)
抗原
See all SPOP-B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SPOP Antibody / Speckle-type POZ protein
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序列
- LHSADQLKTQ AVDFINYHAS DVLE
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids LHSADQLKTQAVDFINYHASDVLE from the human protein were used as the immunogen for the SPOP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SPOP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SPOP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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别名
- SPOP
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背景
- Speckle-type POZ protein is a protein that in humans is encoded by the SPOP gene. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
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UniProt
- O43791
抗原
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