SKIP 抗体
This 小鼠 单克隆 antibody specifically detects SKIP in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7882278
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for SKIP 抗体 (ABIN7882278)
抗原
SKIP
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS)
克隆位点
PCRP-SNW1-2A1
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原理
- SKIP Antibody / SNW1 / NCoA-62
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human protein was used as the immunogen for the SKIP antibody.
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亚型
- IgG2a
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anti-SKIP (C-Term) antibody
适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-SKIP antibody适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SKIP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SKIP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SKIP
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背景
- Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
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UniProt
- Q13573
抗原
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