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SKIP 抗体

The 小鼠 单克隆 anti-SKIP antibody (Clone PCRP-SNW1-2A1) (ABIN7882277) specifically detects SKIP in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7882277
发货至: 中国
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Quick Overview for SKIP 抗体 (ABIN7882277)

抗原

SKIP

适用

  • 4
  • 3
  • 3

宿主

  • 3
  • 1
小鼠

克隆类型

  • 3
  • 1
单克隆

标记

  • 4
非结合性

应用范围

  • 3
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

质量等级

Carrier-free

克隆位点

PCRP-SNW1-2A1
  • 原理

    SKIP Antibody / SNW1 / NCoA-62 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment of human protein was used as the immunogen for the SKIP antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal dilution of the SKIP antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the SKIP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    SKIP

    背景

    Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

    UniProt

    Q13573
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