STAT5A 抗体
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北京 101111
Quick Overview for STAT5A 抗体 (ABIN7882271)
抗原
See all STAT5A 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- STAT5A Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Protein domain of STAT5A was used as the immunogen for the STAT5A antibody.
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亚型
- IgG2c
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anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibody
STAT5A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc) 宿主: 兔 Monoclonal 6E5 unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 583-794) antibodySTAT5A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6D4 unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-794) antibodySTAT5A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 744-794) antibodySTAT5A 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR124H unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 1-104) antibodySTAT5A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (AA 635-794) antibodySTAT5A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) antibodyKD Validated STAT5A 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB1920 unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibodySTAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pTyr694) antibodySTAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibodySTAT5A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the STAT5A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the STAT5A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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别名
- STAT5A
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背景
- Signal transducer and activator of transcription 5A (Stat5a) and Stat5b, which share 96 % homology, undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus, where they initiate transcription. Activation of Stat5a via IL-2, IL-3, IL-7/ GM-CSF, erythropoietin, thrombopoietin and growth hormones influences proliferation, differentiation and apoptosis in lymphohematopoietic cells. Phosphorylation of Stat5a at Ser127/Ser128 and Ser779 are contigent on ErbB-4- mediated activation of Stat5a. Activation of Stat5b via IL-2, IL-4, CSF-1 and growth hormones influences TCR signaling, apoptosis, adult mammary gland development and sexual dimorphism of liver gene expression. Stat5b is the major liver-expressed Stat5 form that has been shown to fuse with the retinoic acid receptor a gene in acute promyelocytic leukemias (APLL). Stat5a/b null mice have severely impaired lymphoid development and differentiation.
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UniProt
- P42229
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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