Recombinant RPS6KA3 抗体
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北京 101111
Quick Overview for Recombinant RPS6KA3 抗体 (ABIN7882175)
抗原
See all RPS6KA3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- RSK2 Antibody / RPS6KA3 / Ribosomal protein S6 kinase alpha 3
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纯化方法
- Affinity chromatography
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免疫原
- A synthetic peptide derived from human RSK2 / RPS6KA3 was used as the immunogen for the RSK2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RSK2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the RSK2 antibody at -20oC.
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- RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
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别名
- RSK2
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背景
- Ribosomal protein S6 kinase alpha 3 (RPS6KA3, RSK2) is a serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. [UniProt]
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UniProt
- P51812
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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