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Reticulon 4 抗体

The 兔 多克隆 anti-Reticulon 4 antibody is suitable to detect Reticulon 4 in samples from 人 和 小鼠. It has been validated for WB, FACS, IHC (p) 和 IF.
产品编号 ABIN7882153
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Reticulon 4 抗体 (ABIN7882153)

抗原

See all Reticulon 4 (RTN4) 抗体
Reticulon 4 (RTN4)

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Reticulon 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 原理

    Nogo A Antibody / RTN4 / Reticulon 4

    序列

    VSNNILHNQQ ELPTALTKLV

    纯化方法

    Affinity purified

    免疫原

    Amino acids VSNNILHNQQELPTALTKLV from the human protein were used as the immunogen for the Nogo A antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Nogo A antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Nogo A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Reticulon 4 (RTN4)

    别名

    Nogo A

    背景

    Human neurite outgrowth inhibitor (NOGO) cDNAs encodes 3 splice variants: NOGOA, NOGOB and NOGOC. The longest cDNA, designated NOGOA, has an open reading frame of 1192 amino acids. It is a potent inhibitor of neurite growth and an IN-1 antigen produced by oligodendrocytes, and may allow the generation of new reagents to enhance CNS regeneration and plasticity. Nogo-A, a member of the Reticulon family, is expressed by oligodendrocytes and associates primarily with the endoplasmic reticulum. The acidic amino terminus of Nogo-A is detected at the cytosolic face of cellular membranes and may contribute to inhibition of axon regeneration at sites of oligodendrocyte injury. A multivalent form of the N terminus of Nogo-A affects the morphology of both neurons and other cell types.

    UniProt

    Q9NQC3

    途径

    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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