Reticulon 4 抗体
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- 抗原 See all Reticulon 4 (RTN4) 抗体
- Reticulon 4 (RTN4)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Reticulon 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-Nogo A/B Antibody is sera. A BLAST analysis was used to suggest cross-reactivity with Anti-Nogo-A B from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Nogo-A B from other sources has not been determined.
- 免疫原
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Immunogen: Nogo-A/B Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic sequence corresponding to internal Nogo-A human protein.
Immunogen Type: Peptide
- Top Product
- Discover our top product RTN4 Primary Antibody
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- 应用备注
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-Nogo A/B Antibody is suitable for use in IHC (p) and WB. Expect a band approximately 48-50 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:500-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store Nogo A B antibody at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- Reticulon 4 (RTN4)
- 别名
- Nogo-A B (RTN4 产品)
- 别名
- ASY antibody, NI220/250 antibody, NOGO antibody, NOGO-A antibody, NOGOC antibody, NSP antibody, NSP-CL antibody, Nbla00271 antibody, Nbla10545 antibody, Nogo-B antibody, Nogo-C antibody, RTN-X antibody, RTN4-A antibody, RTN4-B1 antibody, RTN4-B2 antibody, RTN4-C antibody, RTN4-Cw antibody, DKFZp459C0314 antibody, 1110020G17Rik antibody, AA407876 antibody, AA409940 antibody, AA960376 antibody, C130026I10Rik antibody, NgA antibody, Nogo-A antibody, mKIAA0886 antibody, mKIAA4153 antibody, NI-250 antibody, Nogo antibody, Vp20 antibody, r antibody, rat N antibody, rat NogoA antibody, reticulon-4 antibody, nogo antibody, rtn4 antibody, wu:fb17a02 antibody, wu:fb22f12 antibody, wu:fd61a07 antibody, zgc:92163 antibody, reticulon 4 antibody, reticulon 4a antibody, RTN4 antibody, rtn4 antibody, Rtn4 antibody, rtn4a antibody
- 背景
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Synonyms: KIAA0886, NOGO, Reticulon-4, Foocen, Neurite outgrowth inhibitor, Nogo protein, Neuroendocrine-specific protein, NSP, Neuroendocrine-specific protein C homolog, RTN-x, Reticulon-5
Background: Nogo B 1/2 is a novel myelin-associated, intermediate-length splice variant of Nogo belonging to the reticulon family. It is a multi domain neurite growth inhibitory protein containing several discrete regions with growth inhibitory functions and is a component of the CNS myelin that prevents axonal regeneration in the adult vertebrate CNS. Nogo B1/2 along with NGBR mediated chemotaxis in HUVECs and induced tube formation in 3-dimensional cultures. It is mostly found in intact blood vessels, smooth muscle cells, and endothelial cell, with its N-terminus oriented extracellularly and is a regulator of vascular homeostasis and remodeling. It plays an important role in sporadic and familial amyotrophic lateral sclerosis. Anti-Nogo A/B is ideal for researchers interested in Neurobiology research.
Gene Name: RTN4
- 基因ID
- 57142
- NCBI登录号
- NP_008939
- UniProt
- Q9NQC3
- 途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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