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RAD21 抗体

The 兔 单克隆 anti-RAD21 antibody is suitable to detect RAD21 in samples from 人. It has been validated for WB.
产品编号 ABIN7882129
发货至: 中国
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Room 801-803
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Quick Overview for RAD21 抗体 (ABIN7882129)

抗原

See all RAD21 抗体
RAD21 (RAD21 Homolog (RAD21))

适用

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宿主

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克隆类型

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单克隆

标记

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This RAD21 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

CBH-18
  • 原理

    Rad21 Antibody

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Rad21 was used as the immunogen for the Rad21 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Rad21 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the Rad21 antibody at -20oC.
  • 抗原

    RAD21 (RAD21 Homolog (RAD21))

    别名

    Rad21

    背景

    Double-strand-break repair protein rad21 homolog' is a cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway. [UniProt]

    UniProt

    O60216

    途径

    Positive Regulation of Endopeptidase Activity
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