POGLUT1 抗体
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北京 101111
Quick Overview for POGLUT1 抗体 (ABIN7882078)
抗原
See all POGLUT1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- POGLUT1 Antibody / CLP46 / Rumi
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序列
- KTDLSNVQEL LQFVKANDDV AQEIAER
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纯化方法
- Affinity purified
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免疫原
- Amino acids KTDLSNVQELLQFVKANDDVAQEIAER from the human protein were used as the immunogen for the POGLUT1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the POGLUT1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the POGLUT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
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别名
- POGLUT1
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背景
- This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
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UniProt
- Q8NBL1
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途径
- Notch Signaling
抗原
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