POMC 抗体
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北京 101111
Quick Overview for POMC 抗体 (ABIN7882052)
抗原
See all POMC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- POMC Antibody / ACTH
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human POMC was used as the immunogen for the POMC antibody.
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亚型
- IgG
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anti-Proopiomelanocortin (POMC) (C-Term) antibody
Verified POMC 适用: 人 IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (N-Term) antibodyPOMC 适用: 人, 小鼠, 大鼠 IHC, ELISA, FACS, IF 宿主: 小鼠 Monoclonal 57 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D2B5 unconjugated
anti-Proopiomelanocortin (POMC) antibodyPOMC 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 205-267) antibodyPOMC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-267) antibodyPOMC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proopiomelanocortin (POMC) (AA 1-150) antibodyPOMC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D3A10 unconjugated
anti-Proopiomelanocortin (POMC) (AA 138-176), (Middle Region) antibodyPOMC 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the POMC antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the POMC antibody at -20oC.
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- POMC (Proopiomelanocortin (POMC))
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别名
- POMC
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背景
- This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [RefSeq]
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UniProt
- P01189
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
抗原
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