OCT4 抗体
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北京 101111
Quick Overview for OCT4 抗体 (ABIN7882020)
抗原
See all OCT4 (POU5F1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- POU5F1 Antibody / Oct4
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序列
- ENLQEICKAE TLVQARK
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids ENLQEICKAETLVQARK from the human protein were used as the immunogen for the POU5F1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the POU5F1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the POU5F1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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别名
- POU5F1
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背景
- Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene. It is mapped to 6p21.33. This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
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UniProt
- Q01860
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途径
- Stem Cell Maintenance
抗原
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