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OCT4 抗体

This 兔 多克隆 antibody specifically detects OCT4 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7882020
发货至: 中国
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Room 801-803
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Quick Overview for OCT4 抗体 (ABIN7882020)

抗原

See all OCT4 (POU5F1) 抗体
OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

适用

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  • 4
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人, 小鼠, 大鼠

宿主

  • 140
  • 32
  • 3
  • 1

克隆类型

  • 104
  • 70
  • 1
多克隆

标记

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This OCT4 antibody is un-conjugated

应用范围

  • 128
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Western Blotting (WB)
  • 原理

    POU5F1 Antibody / Oct4

    序列

    ENLQEICKAE TLVQARK

    纯化方法

    Antigen affinity purified

    免疫原

    Amino acids ENLQEICKAETLVQARK from the human protein were used as the immunogen for the POU5F1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the POU5F1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the POU5F1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

    别名

    POU5F1

    背景

    Oct-4 (octamer-binding transcription factor 4), also known as POU5F1 (POU domain, class 5, transcription factor 1), is a protein that in humans is encoded by the POU5F1 gene. It is mapped to 6p21.33. This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

    UniProt

    Q01860

    途径

    Stem Cell Maintenance
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