Recombinant POLG 抗体
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北京 101111
Quick Overview for Recombinant POLG 抗体 (ABIN7881999)
抗原
See all POLG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- POLG Antibody / DNA polymerase subunit gamma 1
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纯化方法
- Affinity chromatography
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免疫原
- A peptide sequence specific to DNA polymerase subunit gamma 1 was used as the immunogen for the POLG antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the POLG antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the POLG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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别名
- POLG
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背景
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DNA polymerase subunit gamma 1 (POLG) is the catalytic subunit of the mitochondrial DNA polymerase complex, responsible for replication and repair of mitochondrial DNA. POLG ensures accurate DNA synthesis within mitochondria, which is essential for proper oxidative phosphorylation and cellular energy production.
Mutations in POLG are associated with a range of mitochondrial disorders, including progressive external ophthalmoplegia, Alpers-Huttenlocher syndrome, and ataxia-neuropathy syndromes. Studying POLG function helps researchers understand mitochondrial genome maintenance and the molecular basis of mitochondrial diseases.
Using a high-quality POLG antibody allows for sensitive detection of the protein in assays such as western blot, immunohistochemistry, and immunofluorescence. A POLG antibody from NSJ Bioreagents offers consistent performance, supporting studies in mitochondrial biology, genetic disorders, and DNA repair mechanisms. Choosing the right POLG antibody is critical for producing reliable and reproducible research results.
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UniProt
- P54098
抗原
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