Patched 2 抗体
The 兔 多克隆 anti-Patched 2 antibody (ABIN7881908) specifically detects Patched 2 in WB, IF 和 IHC (p).
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7881908
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Room 801-803
Quick Overview for Patched 2 抗体 (ABIN7881908)
抗原
See all Patched 2 (PTCH2) 抗体
Patched 2 (PTCH2)
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This Patched 2 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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原理
- Patched 2 Antibody / PTCH2
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序列
- FDYAHSQRAL FDLHQR
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纯化方法
- Affinity purified
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免疫原
- Amino acids FDYAHSQRALFDLHQR from the human protein were used as the immunogen for the Patched 2 antibody.
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亚型
- IgG
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anti-Patched 2 (PTCH2) (AA 793-951) antibody
PTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Patched 2 (PTCH2) (AA 362-411) antibodyPTCH2 适用: 人, Cow, 犬, 马, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Patched 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Patched 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Patched 2 (PTCH2)
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别名
- Patched 2
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背景
- PTCH2 (patched 2), also known as PTC2, encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product. The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages. The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes. Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome. With age, homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia, suggesting a role for Ptch2 in adult epidermal homeostasis via Shh signaling.
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UniProt
- Q9Y6C5
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途径
- Hedgehog Signaling
抗原
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