ODC1 抗体
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北京 101111
Quick Overview for ODC1 抗体 (ABIN7881883)
抗原
See all ODC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Ornithine Decarboxylase Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Recombinant human protein was used as the immunogen for this ODC-1 antibody.
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亚型
- IgG1, kappa
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应用备注
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The optimal dilution of the Ornithine Decarboxylase antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Ornithine Decarboxylase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- ODC1 (Ornithine Decarboxylase 1 (ODC1))
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别名
- Ornithine Decarboxylase
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背景
- Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
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UniProt
- P11926
抗原
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