NFIA 抗体
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北京 101111
Quick Overview for NFIA 抗体 (ABIN7881835)
抗原
See all NFIA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NFIA Antibody / Nuclear Factor 1 A
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant protein fragment was used as the immunogen for the NFIA antibody.
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亚型
- IgG2c
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应用备注
- Optimal dilution of the NFIA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NFIA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NFIA (Nuclear Factor I/A (NFIA))
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别名
- NFIA
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背景
- Nuclear factor (NF) proteins are a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain, and activates transcription through a putatively novel, proline-rich, carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, -globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
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UniProt
- Q12857
抗原
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