NME1 抗体
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北京 101111
Quick Overview for NME1 抗体 (ABIN7881819)
抗原
See all NME1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- NME1 Antibody / NM23A
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human NM23A / NME1 was used as the immunogen for the NME1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NME1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the NME1 antibody at -20oC.
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- NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))
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别名
- NME1
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背景
- This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [RefSeq]
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UniProt
- P15531
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途径
- Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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