Nidogen 抗体
This 大鼠 单克隆 antibody specifically detects Nidogen in ELISA. It exhibits reactivity toward 小鼠.
产品编号 ABIN7881810
发货至:
中国
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Quick Overview for Nidogen 抗体 (ABIN7881810)
抗原
Nidogen (NID)
适用
小鼠
宿主
大鼠
克隆类型
单克隆
标记
This Nidogen antibody is un-conjugated
应用范围
ELISA
克隆位点
ELM1
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原理
- Nidogen Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A murine EHS laminin preparation was used as the immunogen for the Nidogen antibody.
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亚型
- IgG2a, kappa
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anti-Nidogen (NID) (AA 971-1219) antibody
NID 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Nidogen antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Nidogen antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Nidogen (NID)
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别名
- Nidogen
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背景
- Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation. This MAb does not cross-react with other basement membrane components or fibronectin.
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UniProt
- P10493
抗原
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