MUC2 抗体
Our Local Distributor
北京 101111
Quick Overview for MUC2 抗体 (ABIN7881672)
抗原
See all MUC2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- MUC2 Antibody
-
序列
- KYPTTTPIST TTMVTPTPTP TGTQTPTTT
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Amino acids KYPTTTPISTTTMVTPTPTPTGTQTPTTT from the human protein were used as the immunogen for this MUC2 antibody.
-
亚型
- IgG1, kappa
-
-
-
-
应用备注
-
The optimal dilution of the MUC2 antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the MUC2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
-
别名
- MUC2
-
背景
- Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon, in about 65 % of colonic carcinomas and about 40 % of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
-
UniProt
- Q02817
抗原
-