MAP4K3 抗体
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北京 101111
Quick Overview for MAP4K3 抗体 (ABIN7881655)
抗原
See all MAP4K3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MAP4K3 Antibody / MEKKK3 / GLK
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纯化方法
- Purified
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免疫原
- Recombinant human protein was used as the immunogen for the MAP4K3 antibody.
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亚型
- IgM, kappa
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应用备注
- The stated application concentrations are suggested starting points. Titration of the MAP4K3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the MAP4K3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3 (MAP4K3))
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别名
- MAP4K3
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背景
- This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3).
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UniProt
- Q8IVH8
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途径
- MAPK Pathway
抗原
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