MBD1 抗体
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北京 101111
Quick Overview for MBD1 抗体 (ABIN7881627)
抗原
See all MBD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MBD1 Antibody
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序列
- DLTLFDFKQG ILCYPAPKAH PVAVASKKRK
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纯化方法
- Affinity purified
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免疫原
- Amino acids DLTLFDFKQGILCYPAPKAHPVAVASKKRK from the human protein were used as the immunogen for the MBD1 antibody.
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亚型
- IgG
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anti-Methyl-CpG Binding Domain Protein 1 (MBD1) antibody
KD Validated MBD1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB405 unconjugated Recombinant Antibody
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-508) antibodyMBD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-508) antibodyMBD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 1-605) antibodyMBD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 376-405), (C-Term) antibodyMBD1 适用: 人 WB 宿主: 兔 Polyclonal RB2371 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 犬, 小鼠, Cow, 豚鼠, 马, 兔, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 106-355) antibodyMBD1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (N-Term) antibodyMBD1 适用: 人 WB, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MBD1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MBD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
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别名
- MBD1
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背景
- MBD1 (Methyl-CpG-Binding Domain Protein 1), also known as PCM1 or CXXC3, is a protein that in humans is encoded by the MBD1 gene. Using PCR on a hybrid panel and FISH, Hendrich et al.(1999) mapped the MBD1 gene to chromosome 18q21, 2.1 cM distal to MBD2. Using yeast 2-hybrid analysis, reciprocal immunoprecipitation analysis, and protein pull-down assays, Fujita et al.(2003) showed that MBD1 interacted directly with MCAF. Deletion analysis revealed that the C-terminal transcriptional repressor domain(TRD) of MBD1 interacted with a conserved C-terminal domain of MCAF. Reporter gene assays showed that MCAF increased the repressive function of the isolated TRD of MBD1 against SP1. Chromatin immunoprecipitation analysis revealed that MBD1 linked MCAF to methylated promoters. Uchimura et al.(2006) found that MBD1 was multiply sumoylated in HeLa cells. Sumoylation did not alter the intracellular localization of MBD1 at nuclear foci in C-33A human cervical cancer cells.
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UniProt
- Q9UIS9
抗原
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