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MMP2 抗体

The 兔 单克隆 anti-MMP2 antibody (Clone BBA-13) (ABIN7881560) specifically detects MMP2 in WB 和 IHC (p). The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7881560
发货至: 中国
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北京 101111
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Quick Overview for MMP2 抗体 (ABIN7881560)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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  • 50
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  • 1
人, 大鼠

宿主

  • 152
  • 61

克隆类型

  • 127
  • 86
单克隆

标记

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  • 1
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This MMP2 antibody is un-conjugated

应用范围

  • 168
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  • 57
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  • 27
  • 18
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  • 4
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

BBA-13
  • 原理

    MMP2 Antibody

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human MMP2 was used as the immunogen for the MMP2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the MMP2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the MMP2 antibody at -20oC.
  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2

    背景

    The MMP2 gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. [RefSeq]

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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