MIF 抗体
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北京 101111
Quick Overview for MIF 抗体 (ABIN7881523)
抗原
See all MIF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Macrophage migration inhibitory factor Antibody / MIF
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human protein was used as the immunogen for the Macrophage migration inhibitory factor antibody.
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亚型
- IgG
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anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 3-111) antibody
MIF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) antibodyMIF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-115) antibodyMIF 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2A10-4D3 unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-115) antibodyMIF 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) antibodyMIF 适用: 人 WB, ELISA, IHC (p), IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 51-115) antibodyMIF 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (C-Term) antibodyVerified MIF 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-115) antibodyMIF 适用: 人 WB, IHC, FACS, ICC 宿主: 兔 Monoclonal BLR141J unconjugated Recombinant Antibody
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (Internal Region) antibodyMIF 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 2-115) antibodyMIF 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Macrophage migration inhibitory factor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Macrophage migration inhibitory factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))
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别名
- Macrophage migration inhibitory factor
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背景
- Macrophage migration inhibitory factor, also known as MIF or glycosylation inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor Alpha (TNF-Alpha), interleukin-1 (IL-1) and interferon-Gamma (IFN-Gamma). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
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UniProt
- P14174
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
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