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Recombinant LAT 抗体

The 兔 单克隆 anti-LAT antibody (Clone 28L72) (ABIN7881473) specifically detects LAT in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7881473
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant LAT 抗体 (ABIN7881473)

抗原

See all LAT 抗体
LAT (Linker For Activation of T Cells (LAT))

抗体类型

Recombinant Antibody

适用

  • 139
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宿主

  • 133
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克隆类型

  • 114
  • 32
单克隆

标记

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This LAT antibody is un-conjugated

应用范围

  • 104
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Western Blotting (WB)

克隆位点

28L72
  • 原理

    LAT Antibody / Linker for Activation of T cells

    纯化方法

    Affinity chromatography

    免疫原

    A synthetic peptide from human LAT protein was used as the immunogen for the LAT antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the LAT antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the LAT antibody at -20oC.
  • 抗原

    LAT (Linker For Activation of T Cells (LAT))

    别名

    LAT

    背景

    Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. [UniProt]

    UniProt

    O43561

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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