IDH2 抗体
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Quick Overview for IDH2 抗体 (ABIN7881332)
抗原
See all IDH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IDH2 Antibody
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序列
- KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR
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纯化方法
- Affinity purified
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免疫原
- Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR from the human protein were used as the immunogen for the IDH2 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the IDH2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IDH2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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别名
- IDH2
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背景
- Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
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UniProt
- P48735
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途径
- Warburg Effect
抗原
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